Testing for the prostate cancer gene 3 (PCA3) in urine may improve screening for prostate cancer, new research suggests.
Screening for prostate cancer usually involves measuring a protein in the blood called prostate specific antigen or PSA. High PSA levels suggest that cancer may be present and a biopsy is then performed to confirm the diagnosis.
Unlike PSA, which can be elevated with benign as well as malignant prostate disease, PCA3 appears to be specific for prostate cancer, according to the report in the journal Urology. In the present study, Marks' team assessed the ability of urine PCA3 testing to detect prostate cancer in 233 men with elevated PSA levels and at least one prior negative prostate biopsy.
Read full story at the Prostate Cancer Foundation.
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